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Boundless Biology
Gene Expression
Biology Textbooks Boundless Biology Gene Expression
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Section 5

Cancer and Gene Regulation

Book Version 32
By Boundless
Boundless Biology
Biology
by Boundless
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5 concepts
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Altered Gene Expression in Cancer

Cancer, a disease of altered gene expression, is the result of gene mutations or dramatic changes in gene regulation.

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Epigenetic Alterations in Cancer

Common in cancer cells, silencing genes, which occur through epigenetic mechanisms, include modifications to histone proteins and DNA.

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Cancer and Transcriptional Control

Increased transcriptional activation of genes result in alterations of cell growth leading to abnormal gene expression, as seen in cancer.

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Cancer and Post-Transcriptional Control

Modifications, such as the overexpression of miRNAs, in the post-transcriptional control of a gene can result in cancer.

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Cancer and Translational Control

Cancer can arise from translational or post-translational modifications of proteins.

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