renin

(noun)

a circulating enzyme released by mammalian kidneys that converts angiotensinogen to angiotensin-I that plays a role in maintaining blood pressure

Related Terms

  • aldosterone
  • osmoreceptor
  • aquaporin
  • angiotensin
  • antidiuretic hormone
  • mineralocorticoid
  • electrolyte

Examples of renin in the following topics:

  • Other Hormonal Controls for Osmoregulation

    • The renin-angiotensin-aldosterone system (RAAS) stabilizes blood pressure and volume via the kidneys, liver, and adrenal cortex.
    • The renin-angiotensin-aldosterone system (RAAS) is a hormone system that regulates blood pressure and water (fluid) balance .
    • Defective renin production can cause a continued decrease in blood pressure and cardiac output.
    • Its actions suppress the actions of aldosterone, ADH, and renin.
    • The renin-angiotensin-aldosterone system increases blood pressure and volume.
  • Hormonal Regulation of the Excretory System

    • When blood pressure drops, the renin-angiotensin-aldosterone system (RAAS) is activated.
    • Cells in the juxtaglomerular apparatus, which regulates the functions of the nephrons of the kidney, detect this and release renin.
    • Renin, an enzyme, circulates in the blood, reacting with a plasma protein produced by the liver called angiotensinogen.
    • When angiotensinogen is cleaved by renin, it produces angiotensin I, which is then converted into angiotensin II in the lungs.
    • Angiotensin II, in turn, is formed when renin cleaves angiotensin.
  • Organs with Secondary Endocrine Functions

    • ANP also reduces the amounts of renin released by the kidneys and aldosterone released by the adrenal cortex, further preventing the retention of water.
    • Renin, released in response to decreased blood volume or pressure, is part of the renin-angiotensin-aldosterone system that leads to the release of aldosterone.
  • Epinephrine and Norepinephrine

    • These hormones go one step further and trigger the renin-angiotensin-aldosterone system, the hormone system that regulates blood pressure and water (fluid) imbalance.
  • Adrenal Glands

    • If sodium levels are low in the blood, the kidney secretes more renin, an enzyme that stimulates the formation of angiotensin from a molecule made from the liver.
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