luteinizing hormone

(noun)

a hormone, produced by part of the pituitary gland, that stimulates ovulation and the development of the corpus luteum in female mammals, and the production of androgens by male mammals

Related Terms

  • androgen
  • testosterone
  • follicle stimulating hormone
  • gonad
  • gonadotropin-releasing hormone
  • Leydig cell
  • prolactin
  • inhibin
  • Sertoli cell
  • puberty

Examples of luteinizing hormone in the following topics:

  • Male Hormones

    • The onset of puberty is controlled by two major hormones: FSH initiates spermatogenesis and LH signals the release of testosterone.
    • These changes are largely influenced by hormonal activity.
    • Hormones play an organizational role, priming the body to behave in a certain way once puberty begins, and an activational role, referring to changes in hormones during adolescence that trigger behavioral and physical changes.
    • At the onset of puberty, the hypothalamus begins secreting high pulses of GnRH, or gonadotropin-releasing hormone.
    • In response, the pituitary gland releases follicle stimulating hormone (FSH) and luteinizing hormone (LH) into the male system for the first time.
  • Hypothalamic-Pituitary Axis

    • The anterior pituitary produces seven hormones: growth hormone (GH), prolactin (PRL), thyroid-stimulating hormone (TSH), melanin-stimulating hormone (MSH), adrenocorticotropic hormone (ACTH), follicle-stimulating hormone (FSH), and luteinizing hormone (LH).
    • Anterior pituitary hormones are sometimes referred to as tropic hormones because they control the functioning of other organs.
    • While these hormones are produced by the anterior pituitary, their production is controlled by regulatory hormones produced by the hypothalamus.
    • These regulatory hormones can be releasing hormones or inhibiting hormones, causing more or less of the anterior pituitary hormones to be secreted.
    • Negative feedback then regulates how much of these regulatory hormones are released and how much anterior pituitary hormone is secreted.
  • Hormonal Regulation of the Reproductive System

    • During puberty, in both males and females, the hypothalamus produces gonadotropin-releasing hormone (GnRH), which stimulates the production and release of follicle stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary gland.
    • FSH production is inhibited by the hormone inhibin, which is released by the testes.
    • It is also called interstitial-cell-stimulating hormone.
    • Prolactin levels are regulated by the hypothalamic hormones, prolactin-releasing hormone (PRH) and prolactin-inhibiting hormone (PIH) (which is now known to be dopamine).
    • Hormonal regulation of the female reproductive system involves hormones from the hypothalamus, pituitary, and ovaries.
  • Female Hormones

    • The stages of the ovarian cycle in the female are regulated by hormones secreted by the hypothalamus, pituitary, and the ovaries.
    • As with the male, the hypothalamic hormone GnRH (gonadotropin-releasing hormone) causes the release of the hormones FSH (follicle stimulating hormone) and LH (luteinizing hormone) from the anterior pituitary.
    • Follicle cells produce the hormone inhibin, which inhibits FSH production.
    • Estradiol and progesterone are steroid hormones that prepare the body for pregnancy.
    • Rising and falling hormone levels result in progression of the ovarian and menstrual cycles.
  • Lipid-Derived, Amino Acid-Derived, and Peptide Hormones

    • All hormones in the human body can be divided into lipid-derived, amino acid-derived, and peptide hormones.
    • One of the key, distinguishing features of lipid-derived hormones is that they can diffuse across plasma membranes whereas the amino acid-derived and peptide hormones cannot.
    • The primary class of lipid hormones in humans is the steroid hormones.
    • Examples of steroid hormones include estradiol, which is an estrogen, or female sex hormone, and testosterone, which is an androgen, or male sex hormone.
    • The structures of peptide hormones (a) oxytocin, (b) growth hormone, and (c) follicle-stimulating hormone are shown.
  • Humoral, Hormonal, and Neural Stimuli

    • The release of hormones can be triggered by changes in the blood ("humor"), by the actions of other hormones, or by neurological stimuli.
    • Hormonal stimuli refers to the release of a hormone in response to another hormone.
    • A number of endocrine glands release hormones when stimulated by hormones released by other endocrine glands.
    • The anterior pituitary, in turn, releases hormones that regulate hormone production by other endocrine glands.
    • The hypothalamus stimulates the anterior pituitary gland, via hormones, to release thyroid-stimulating hormone (TSH).
  • How Hormones Work

    • Hormones are chemical messengers that relay messages to cells that display specific receptors for each hormone and respond to the signal.
    • All multicellular organisms produce hormones; plant hormones are also called phytohormones.
    • Hormones mediate changes in target cells by binding to specific hormone receptors.
    • Cells can have many receptors for the same hormone, but often also possess receptors for different types of hormones.
    • Cells respond to a hormone when they express a specific receptor for that hormone.
  • Plasma Membrane Hormone Receptors

    • Amino acid-derived hormones and polypeptide hormones are not lipid-derived (lipid-soluble or fat-soluble); therefore, they cannot diffuse through the plasma membrane of cells.
    • Lipid-insoluble hormones bind to receptors on the outer surface of the plasma membrane, via plasma membrane hormone receptors.
    • Unlike steroid hormones, lipid-insoluble hormones do not directly affect the target cell because they cannot enter the cell and act directly on DNA.
    • The effect of a hormone is amplified as the signaling pathway progresses.
    • Describe the events that occur when a hormone binds to a plasma hormone receptor
  • Hormone Functions

    • The endocrine system plays a role in growth, metabolism, and other processes by releasing hormones into the blood.
    • An animal's endocrine system controls body processes through the production, secretion, and regulation of hormones.
    • Target cells, those having a receptor for a signal, respond to a hormone when they express a specific receptor for that hormone.
    • Different tissue types may also respond differently to the same hormonal signal.
    • By releasing hormones, the endocrine system plays a role in growth, metabolism, and sexual development.
  • Hormonal Responses to Food

    • The system is made of a series of glands that produce chemicals called hormones.
    • One of the important factors under hormonal control is the stomach acid environment.
    • Secretin acts in tandem with another hormone called cholecystokinin (CCK).
    • Another level of hormonal control occurs in response to the composition of food.
    • Scientists are exploring the role of each hormone in the digestive process and developing ways to target these hormones.
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