fibroblast

Examples of fibroblast in the following topics:

• Connective Tissues: Loose, Fibrous, and Cartilage

  • The principal cell of connective tissues is the fibroblast, an immature connective tissue cell that has not yet differentiated.
  • Fibroblasts are motile, able to carry out mitosis, and can synthesize whichever connective tissue is needed.
  • Loose connective tissue has some fibroblasts, although macrophages are present as well.
  • The fibers and other components of the connective tissue matrix are secreted by fibroblasts.

• Bone Remodeling and Repair

  • Though fragments of the blood clot may remain, fibroblasts and osteoblasts enter the area and begin to reform bone.
  • Fibroblasts produce collagen fibers that connect the broken bone ends, while osteoblasts start to form spongy bone.

• Chromosomal Structural Rearrangements

  • Interestingly, humans and chimpanzees express USP14 at distinct levels in specific cell types, including cortical cells and fibroblasts.

• Establishing Body Axes during Development

  • Other factors shown to provide positional information to the neural progenitor cells include Fibroblast growth factors (FGF) and Retinoic Acid.

• Connective Tissues: Bone, Adipose, and Blood

  • Adipose tissue, or fat tissue, is considered a connective tissue even though it does not have fibroblasts or a real matrix, and has only a few fibers.