chondrocyte

Examples of chondrocyte in the following topics:

• Growth of Bone

  • The reserve zone, the region closest to the epiphyseal end of the plate, contains small chondrocytes within the matrix .
  • The proliferative zone, the next layer toward the diaphysis, contains stacks of slightly-larger chondrocytes .
  • It continually makes new chondrocytes via mitosis.
  • The zone of maturation and hypertrophy contains chondrocytes that are older and larger than those in the proliferative zone .
  • The second zone, the proliferative zone, is where chondrocytes are continually undergoing mitosis.

• Connective Tissues: Loose, Fibrous, and Cartilage

  • The cells, called chondrocytes (mature cartilage cells), make the matrix and fibers of the tissue.
  • Chondrocytes are found in spaces within the tissue called "lacunae. "
  • Hyaline cartilage consists of a matrix with cells called chondrocytes (shown here) embedded in it.
  • The chondrocytes exist in cavities in the matrix called lacunae.

• Bone Development

  • In long bones, chondrocytes form a template of the hyaline cartilage diaphysis.
  • This calcification prevents diffusion of nutrients into the matrix, resulting in chondrocytes dying and the opening up of cavities in the diaphysis cartilage.

• Hormonal Regulation of Growth

  • Thus, GH exerts some of its effects by binding to receptors on target cells, where it activates a pathway that directly stimulates division and multiplication of chondrocytes of cartilage.
  • IGF-1 also has stimulatory effects on osteoblast and chondrocyte activity to promote bone growth.